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Dobutamine Hydrochloride Injection

Dobutamine Hydrochloride Injection 

Dobutamine is a medication that treats heart failure by strengthening your heart muscle

Dobutamine Hydrochloride Injection is a medication used for specific medical purposes. Let me provide you with some information about it:

  • Description:

    • Dobutamine Hydrochloride Injection is a synthetic catecholamine.
    • It is a direct-acting inotropic agent that primarily stimulates the β receptors of the heart.
    • Unlike dopamine, it does not cause the release of endogenous norepinephrine.
    • In animal studies, dobutamine produces less increase in heart rate and less decrease in peripheral vascular resistance compared to isoproterenol.
    • In patients with depressed cardiac function, both dobutamine and isoproterenol increase cardiac output to a similar degree.
    • Dobutamine usually increases cardiac output without marked heart rate increases, and the cardiac stroke volume is typically increased.
    • Systemic vascular resistance is usually decreased with dobutamine administration.
    • The onset of action is within 1 to 2 minutes, with peak effects achieved after 10 minutes.
    • The plasma half-life of dobutamine in humans is 2 minutes.
  • Indications and Usage:

    • Dobutamine Injection is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures2.

Remember to consult your healthcare provider for personalized advice, and if you have further questions or need additional information, feel free to ask! 😊

Dobutamine Hydrochloride Injection

  • Strengths

    12.5 mg/ml, 50 mg/ml, 250mg

  • Fill Volumes

    5 ml, 20 ml

  • Container

    Glass Ampoule, Glass Vial, Lyophilized

  • Use

    Dobutamine is a medication that treats heart failure by strengthening your heart muscle

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