Anidulafungin for Injection
Anidulafungin treats fungal or yeast infections
Anidulafungin for Injection is an antifungal medication used to treat severe fungal infections. It kills fungi by preventing them from making their protective covering. Here are some important details about Anidulafungin:
Indications:
Anidulafungin is effective in treating the following infections:
Candidemia and other forms of Candida infections (such as intra-abdominal abscess and peritonitis) in adults and pediatric patients (1 month of age and older).
Esophageal candidiasis in adults.
Limitations of use:
Anidulafungin has not been studied in adult and pediatric patients with endocarditis, osteomyelitis, and meningitis due to Candida or in sufficient numbers of neutropenic patients.
The dosage of Anidulafungin for the treatment of Candida dissemination into the central nervous system (CNS) and the eye has not been established.
Anidulafungin is associated with high relapse rates in esophageal candidiasis.
Dosage and Administration:
For adults:
Candidemia and other Candida infections: A 200 mg loading dose on Day 1, followed by a 100 mg once-daily maintenance dose thereafter for at least 14 days after the last positive culture.
Esophageal candidiasis: A 100 mg loading dose on Day 1, followed by a 50 mg once-daily maintenance dose thereafter for a minimum of 14 days and at least 7 days following symptom resolution.
For pediatric patients (1 month of age and older):
Candidemia and other Candida infections: A 3 mg/kg (not to exceed 200 mg) loading dose on Day 1, followed by a 1.5 mg/kg (not to exceed 100 mg) once-daily maintenance dose thereafter for at least 14 days after the last positive culture.
Rate of Infusion:
The rate of infusion should not exceed 1.1 mg/minute.
Contraindications:
Known hypersensitivity to anidulafungin, any component of ERAXIS (brand name for anidulafungin), or other echinocandins.
Known or suspected Hereditary Fructose Intolerance (HFI).
Remember to consult your healthcare provider for personalized advice regarding the use of Anidulafungin for Injection in your specific situation. 😊