Apomorphine injection is used to treat ''off'' episodes (times of difficulty moving, walking, and speaking that may happen as the medication wears off or at random) in people with advanced Parkinson's disease.
Apomorphine Hydrochloride Injection is a medication used to treat acute, intermittent episodes of poor mobility called “off” episodes (end-of-dose wearing “off” or unpredictable “on-off” episodes) in people with advanced Parkinson’s disease1. It belongs to a class of drugs called dopamine agonists. These medications mimic the action of dopamine, a neurotransmitter that plays a crucial role in movement control. Low levels of dopamine are associated with the symptoms of Parkinson’s disease. Apomorphine works by binding to dopamine receptors in the brain, acting similarly to natural dopamine. There are two forms of apomorphine:
Subcutaneous Injection (Apokyn):
Administered by injecting it under the skin.
Used to manage acute “off” episodes in advanced Parkinson’s disease.
Available as both the brand name Apokyn and a generic version.
Sublingual Film (Kynmobi):
A film placed under the tongue.
Also used for short-term (acute) “off” episodes in Parkinson’s disease.
Currently, generic versions of the sublingual film have not been approved.
It’s important to note that apomorphine is not known to be safe and effective in children. Additionally, certain individuals should avoid using apomorphine, including those taking specific medicines to treat nausea (5HT3 antagonists) and those allergic to apomorphine hydrochloride or its ingredients1. If you experience any allergic reactions, such as hives, itching, rash, or swelling, seek medical attention promptly. Always consult your healthcare provider for personalized advice regarding the use of apomorphine. 😊🌟