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Esomeprazole for Injection

Esomeprazole injection is used to treat conditions where there is too much acid in the stomach.

Esomeprazole sodium for injection is a proton pump inhibitor (PPI) used for specific purposes. Let’s explore more about it:

  • Indications and Usage:

    • Esomeprazole sodium for injection is indicated for the:
      • Short-term treatment of Gastroesophageal Reflux Disease (GERD) with erosive esophagitis (EE) in adults and pediatric patients aged 1 month to 17 years. It serves as an alternative to oral therapy when oral esomeprazole is not feasible or appropriate.
      • Risk reduction of rebleeding of gastric or duodenal ulcers following therapeutic endoscopy for acute bleeding gastric or duodenal ulcers in adults.
  • Dosage and Administration:

    • For GERD with Erosive Esophagitis:
      • The recommended adult dosage is either 20 mg or 40 mg once daily by intravenous injection (no less than 3 minutes) or intravenous infusion (10 minutes to 30 minutes) for up to 10 days.
      • The recommended pediatric dosage varies based on age and weight.
    • For Risk Reduction of Rebleeding of Gastric and Duodenal Ulcers:
      • The recommended adult dosage is 80 mg administered as an intravenous infusion over 30 minutes, followed by a continuous infusion of 8 mg/hour for a total treatment duration of 72 hours.
    • Dosage adjustment is necessary for patients with hepatic impairment.
  • Preparation and Administration:

    • Esomeprazole sodium for injection is available as a lyophilized powder in a single-dose vial for reconstitution.
    • Proper preparation and administration instructions are essential.
  • Contraindications:

    • Patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles.
    • Patients receiving rilpivirine-containing products.
  • Warnings and Precautions:

    • Gastric Malignancy: Symptomatic response to therapy does not exclude the presence of gastric malignancy. Consider additional follow-up and diagnostic testing.
    • Acute Tubulointerstitial Nephritis: Discontinue treatment and evaluate patients.

Remember to consult a healthcare professional for personalized advice regarding the use of Esomeprazole Sodium for Injection. If you have any further questions or need additional information, feel free to ask! 😊

Esomeprazole for Injection

  • Strengths

    20 mg, 40 mg

  • Container

    Glass Vial

  • Use

    Esomeprazole injection is used to treat conditions where there is too much acid in the stomach.

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