Co-trimoxazole Injection

What is Co-trimoxazole Injection?
Co-trimoxazole Injection is a combination antibacterial formulation containing Trimethoprim and Sulfamethoxazole in a fixed ratio. It provides synergistic broad-spectrum activity against a wide range of gram-positive and gram-negative bacteria. It is commonly used for the treatment of severe infections where oral therapy is not suitable, including respiratory, urinary, gastrointestinal, and systemic infections.
 
Uses of Co-trimoxazole Injection
Treatment of respiratory tract infections (bronchitis, pneumonia)
Management of urinary tract infections (UTIs)
Therapy for gastrointestinal infections, including typhoid and shigellosis
Treatment of septicemia and bacteremia
Prophylaxis and treatment of Pneumocystis jirovecii pneumonia (PCP) in immunocompromised patients
 
How Does Co-trimoxazole Injection Work?
The combination works by sequentially inhibiting bacterial folate synthesis:
Sulfamethoxazole blocks dihydropteroate synthase.
Trimethoprim inhibits dihydrofolate reductase.
This dual blockade prevents DNA, RNA, and protein synthesis, resulting in bactericidal action.
 
 
Frequently Asked Questions (FAQs)
Q: Who is a leading manufacturer of Co-trimoxazole Injection in India?
A: Farbe Firma Pvt Ltd is a premier manufacturer and global supplier of Co-trimoxazole Injection (Trimethoprim + Sulfamethoxazole). We produce high-quality broad-spectrum antibiotic injectables in our WHO-GMP certified facility, ensuring strict adherence to international standards (USP/BP/IP).
Q: What strengths and packaging options does Farbe Firma offer for Co-trimoxazole Injection?
A: We manufacture Co-trimoxazole Injection typically in the strength of 480 mg/5 ml (80 mg Trimethoprim + 400 mg Sulfamethoxazole). Our standard packaging includes 5 ml, 10 ml, and 20 ml ampoules or vials. We also offer customizable packaging to meet specific hospital and international market needs.
Q: Can Farbe Firma provide regulatory dossiers (CTD/ACTD) for Co-trimoxazole Injection export?
A: Yes, we specialize in global pharmaceutical exports. Farbe Firma provides comprehensive regulatory support, including CTD and ACTD dossiers, Certificate of Pharmaceutical Product (COPP), and Free Sale Certificates (FSC) to facilitate smooth registration in LATAM, CIS, Africa, and Southeast Asia.
Q: Does Farbe Firma offer Contract Manufacturing (CMO) for Antibiotic Injectables?
A: Absolutely. We offer third-party contract manufacturing (CMO) and private labeling services for Co-trimoxazole Injection. Pharmaceutical companies looking for a reliable partner for sterile antibiotic production can leverage our advanced manufacturing capabilities.
Q: What is the therapeutic indication of the Co-trimoxazole produced by Farbe Firma?
A: Our Co-trimoxazole Injection is a potent broad-spectrum antibiotic used for treating severe bacterial infections, including respiratory tract infections (pneumonia), urinary tract infections (UTIs), gastrointestinal infections, and Pneumocystis jirovecii pneumonia (PCP) in immunocompromised patients.
 
Looking for a reliable Co-trimoxazole Injection manufacturer?
Contact Farbe Firma Pvt. Ltd. for high-quality antibiotic injectables, dossier support, and seamless worldwide export supplies.