Metoclopramide Injection

What is Metoclopramide Injection?
Metoclopramide Injection is a dopamine receptor antagonist with antiemetic and prokinetic properties. It is widely used for the prevention and treatment of nausea and vomiting, including that caused by chemotherapy, radiotherapy, surgery, and gastrointestinal disorders. In addition, it enhances gastric emptying and intestinal motility, making it useful in functional dyspepsia and gastroparesis.
 
Uses of Metoclopramide Injection
Prevention and treatment of nausea and vomiting (post-operative, chemotherapy, radiotherapy)
Management of gastroparesis (delayed gastric emptying)
Adjunct in diagnostic GI procedures (e.g., barium studies, endoscopy)
Relief of migraine-associated nausea
Supportive therapy in gastroesophageal reflux disease (GERD)
 
How Does Metoclopramide Injection Work?
Metoclopramide works by blocking dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the brain, thereby preventing nausea and vomiting. Additionally, it enhances acetylcholine release in the GI tract, improving gastric emptying and intestinal motility.
 
Frequently Asked Questions (FAQs)
Q: What is Metoclopramide Injection used for?
A: Metoclopramide Injection is an antiemetic and prokinetic agent. It is primarily used for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and migraines. It is also used to treat diabetic gastroparesis (delayed stomach emptying) and to facilitate small bowel intubation during diagnostic procedures.
Q: Who is a top manufacturer of Metoclopramide Injection in India?
A: Farbe Firma Pvt. Ltd. is a leading manufacturer and supplier of Metoclopramide Injection (Trade Name: Metosyl). We manufacture this essential gastrointestinal drug in our WHO-GMP certified facility, ensuring high sterility and efficacy for hospitals and clinics globally.
Q: In what strength and packing is Metosyl (Metoclopramide) available?
A: We manufacture Metoclopramide Injection in the standard strength of 5 mg/ml. It is typically available in 2 ml ampoules (10 mg total dose), which is the standard adult dose for intramuscular or intravenous administration.
Q: How does Metoclopramide work?
A: Metoclopramide works by blocking dopamine receptors in the brain's "chemoreceptor trigger zone," which prevents nausea signals. Simultaneously, it acts as a prokinetic in the gut, accelerating gastric emptying and intestinal transit, which helps prevent vomiting and relieves symptoms of gastroparesis.
Q: Do you offer Contract Manufacturing for Metoclopramide Injection?
A: Yes, Farbe Firma Pvt. Ltd. offers specialized Contract Manufacturing (CMO) services for sterile liquid injectables. We provide end-to-end support, including formulation, sterile filling in ampoules, and regulatory dossier compilation (CTD/ACTD) to help you launch the product under your own brand.
 
Looking for a reliable Metoclopramide Injection manufacturer?
Contact Farbe Firma Pvt. Ltd. for high-quality antiemetic & prokinetic injectables, dossier support, and seamless worldwide export supply.