Etanercept Injection

What is Etanercept Injection?
Etanercept Injection is a biologic medication and a potent TNF-blocker. It is a genetically engineered fusion protein that plays a critical role in controlling chronic inflammation. By targeting specific proteins in the immune system, it helps prevent joint damage and skin lesions in patients with debilitating autoimmune conditions, significantly improving their quality of life.
Uses of Etanercept Injection
Rheumatoid Arthritis: To reduce symptoms and inhibit the progression of structural damage in moderate to severe cases.
Plaque Psoriasis: Treatment of adult and pediatric patients with chronic moderate to severe plaque psoriasis.
Ankylosing Spondylitis: To reduce pain and improve physical function in patients with inflammation of the spine.
Psoriatic Arthritis: To improve physical function and reduce joint inflammation.
Polyarticular Juvenile Idiopathic Arthritis: Management of autoimmune arthritis in children aged 2 years and older.
How Does Etanercept Injection Work?
Etanercept works by binding to Tumor Necrosis Factor (TNF), a naturally occurring cytokine that involved in systemic inflammation. In autoimmune diseases, the body produces too much TNF, which attacks healthy tissues. Etanercept acts like a "sponge," soaking up excess TNF and preventing it from binding to cell surface receptors, thereby neutralizing the inflammatory response.
FAQs on Etanercept Injection
1. How is Etanercept Injection typically administered? Etanercept is administered via subcutaneous injection (under the skin), usually in the thigh, abdomen, or upper arm. Depending on the condition being treated, it is typically injected once or twice a week.
2. Can Etanercept be used alongside other medications? Yes, it is often prescribed in combination with methotrexate for the treatment of Rheumatoid Arthritis. However, it should not be used with other biologic DMARDs (like adalimumab or infliximab) due to the increased risk of serious infections.
3. What precautions should be taken before starting treatment? Since Etanercept affects the immune system, patients must be screened for Tuberculosis (TB) and Hepatitis B before starting therapy. It is also important to avoid "live" vaccines while using this medication.
Therapeutic Category
Others (Biologics / Immunomodulators)
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