Caffeine Citrate Injection

What is Caffeine Citrate Injection?
Caffeine Citrate Injection is a sterile, preservative-free respiratory stimulant used primarily in preterm neonates to reduce episodes of apnea. As a selective adenosine receptor antagonist, it improves central respiratory drive and is widely used in NICUs for its proven efficacy and safety profile.
 
Uses of Caffeine Citrate Injection
Management of apnea of prematurity (AOP)
Reduction of apnea/bradycardia episodes in preterm infants
Support during weaning/extubation in neonatal care (as per clinician’s protocol)
Use strictly under physician supervision in hospital/NICU settings
 
How Does Caffeine Citrate Injection Work?
Caffeine citrate blocks adenosine (A1/A2A) receptors in the central nervous system, increasing respiratory drive and sensitivity to CO₂. It enhances diaphragmatic contractility and improves minute ventilation, thereby reducing apnea frequency in preterm infants.
 
Frequently Asked Questions (FAQs)
Q: Who is a leading manufacturer of Caffeine Citrate Injection in India?
A: Farbe Firma Pvt Ltd is a premier manufacturer and global supplier of Caffeine Citrate Injection. We produce high-quality, preservative-free respiratory stimulant injectables in our WHO-GMP certified facility, designed specifically for sensitive neonatal intensive care (NICU) use.
Q: What strengths and packaging options does Farbe Firma offer for Caffeine Citrate Injection?
A: We manufacture Caffeine Citrate Injection primarily in the strength of 20 mg/mL (equivalent to 10 mg/mL caffeine base). Our standard packaging options include 1 mL, 2 mL, and 3 mL ampoules or vials. We offer preservative-free single-dose presentations to ensure safety for preterm infants.
Q: Can Farbe Firma provide regulatory dossiers (CTD/ACTD) for Caffeine Citrate Injection export?
A: Yes, we specialize in global pharmaceutical exports. Farbe Firma provides comprehensive regulatory support, including CTD and ACTD dossiers, stability data (ICH zones), and Certificate of Pharmaceutical Product (COPP) to facilitate smooth registration in LATAM, CIS, Africa, and Southeast Asia.
Q: Does Farbe Firma offer Contract Manufacturing (CMO) for Neonatal Injectables?
A: Absolutely. We offer third-party contract manufacturing (CMO) and private labeling services for Caffeine Citrate Injection. Pharmaceutical companies looking for a reliable partner for sterile neonatal products can leverage our advanced manufacturing capabilities.
Q: What is the therapeutic indication of the Caffeine Citrate produced by Farbe Firma?
A: Our Caffeine Citrate Injection is a respiratory stimulant indicated for the short-term treatment of apnea of prematurity in infants born between 28 and less than 33 weeks of gestational age. It stimulates the central nervous system to improve breathing.
 
Looking for a reliable Caffeine Citrate Injection manufacturer?
Contact Farbe Firma Pvt. Ltd. for dossier support, registration assistance, private labeling, and export supplies.