Streptomycin for Injection

What is Streptomycin for Injection?
Streptomycin for Injection is a potent aminoglycoside antibiotic and was the first antibiotic ever discovered to treat tuberculosis. It is derived from the soil bacterium Streptomyces griseus. In modern medicine, it remains a vital "first-line" medication for TB when used in combination with other drugs, and a critical tool against rare, severe infections that are resistant to more common antibiotics.
Uses of Streptomycin for Injection
Tuberculosis (TB): Part of a multi-drug regimen for the treatment of active TB, especially in cases where resistance is suspected.
Tularemia: Often considered the drug of choice for treating "rabbit fever" caused by Francisella tularensis.
Plague: Effective treatment for Yersinia pestis infections.
Endocarditis: Used in combination with penicillin for treating heart valve infections caused by Enterococcus or Streptococcus.
Other Rare Infections: Treatment of Brucellosis and Burkholderia infections when alternative therapies are not viable.
How Does Streptomycin for Injection Work?
Streptomycin is a bactericidal antibiotic that works by inhibiting protein synthesis. It binds specifically to the 30S subunit of the bacterial ribosome. This binding causes a "misreading" of the genetic code (mRNA), leading to the production of abnormal, non-functional proteins or the total shutdown of protein production. Without the ability to create essential proteins, the bacterial cell wall fails and the bacteria die.
FAQs on Streptomycin for Injection
1. How is Streptomycin typically administered? It is primarily administered via deep intramuscular (IM) injection into a large muscle mass, such as the gluteus. In very specific clinical circumstances, it may be given intravenously (IV), but this is less common and requires very slow infusion to minimize toxicity.
2. What are the "Signature Side Effects" of this drug? Like other aminoglycosides, Streptomycin carries a risk of ototoxicity (damage to hearing and balance) and nephrotoxicity (damage to the kidneys). Patients should be monitored for signs of dizziness, ringing in the ears (tinnitus), or changes in urine output.
3. Is Streptomycin used alone to treat TB? No. To prevent the development of antibiotic resistance, Streptomycin is never used alone for tuberculosis. It is always part of a combination therapy (usually with Isoniazid, Rifampin, and Pyrazinamide) to ensure all bacteria are eradicated.
Therapeutic Category
Anti-Infectives (Aminoglycoside Antibiotic)
Looking for a reliable Streptomycin for Injection manufacturer? Contact Farbe Firma Pvt. Ltd. for dossier support, registration assistance, and export supplies. We provide high-potency anti-infective injectables manufactured under strict WHO-GMP conditions.