Atracurium Besylate Injection

What is Atracurium Besylate Injection?
Atracurium Besylate Injection is a non-depolarizing neuromuscular blocking agent used in anesthesia. It is widely employed to produce skeletal muscle relaxation during surgery, facilitate endotracheal intubation, and support controlled or assisted ventilation. Belonging to the benzylisoquinolinium class, Atracurium is valued for its predictable onset, intermediate duration of action, and organ-independent metabolism, making it safe for patients with renal or hepatic impairment.
 
Uses of Atracurium Besylate Injection
To induce skeletal muscle relaxation during surgical procedures
To facilitate endotracheal intubation
To aid in mechanical ventilation in intensive care settings
 
How Does Atracurium Besylate Injection Work?
Atracurium works by blocking the transmission of nerve impulses to the muscles. It competitively binds to acetylcholine receptors at the neuromuscular junction, preventing depolarization and leading to muscle relaxation. Unlike many neuromuscular blockers, it is degraded mainly by Hofmann elimination, a process independent of kidney and liver function.
 
Frequently Asked Questions (FAQs)
Q: What is Atracurium Besylate Injection used for?
A: Atracurium Besylate Injection is a non-depolarizing neuromuscular blocking agent. It is used as an adjunct to general anesthesia to induce skeletal muscle relaxation during surgery and to facilitate endotracheal intubation. It is also used to aid controlled ventilation in Intensive Care Units (ICU).
Q: Who is a top manufacturer of Atracurium Besylate Injection in India?
A: Farbe Firma Pvt. Ltd. is a leading manufacturer and supplier of Atracurium Besylate Injection (Trade Name: Atrasyl). We manufacture this critical anesthesia injectable in our WHO-GMP certified facility, ensuring consistent quality and organ-independent metabolism suitable for patients with renal or hepatic impairment.
Q: In what strengths and packing is Atrasyl (Atracurium) available?
A: We manufacture Atracurium Besylate Injection in the standard strength of 10 mg/ml. It is available in 2.5 ml (25 mg), 5 ml (50 mg), and 10 ml (100 mg) ampoules or vials, providing flexible dosing options for surgical and ICU requirements.
Q: How does Atracurium Besylate work?
A: Atracurium works by competitively binding to cholinergic receptors on the motor end-plate to block the transmission of nerve impulses, resulting in muscle relaxation. A key advantage is its degradation via Hofmann elimination, which makes it safe for patients with kidney or liver dysfunction.
Q: Do you offer Contract Manufacturing for Atracurium Besylate?
A: Yes, Farbe Firma Pvt. Ltd. offers specialized Contract Manufacturing (CMO) services for Atracurium Besylate Injection. We provide end-to-end support, including cold-chain management (if required), sterile filling, and regulatory dossier compilation (CTD/ACTD) to help you launch the product under your own brand.
 
Looking for a reliable Atracurium Besylate Injection manufacturer? Contact Farbe Firma Pvt. Ltd. for dossier support, registration assistance, and international supply.