Caffeine Citrate Injection – Manufacturer, Exporter & Supplier

What is Caffeine Citrate Injection?
Caffeine Citrate Injection is a sterile, preservative-free respiratory stimulant used primarily in preterm neonates to reduce episodes of apnea. As a selective adenosine receptor antagonist, it improves central respiratory drive and is widely used in NICUs for its proven efficacy and safety profile.
 
Uses of Caffeine Citrate Injection
Management of apnea of prematurity (AOP)
Reduction of apnea/bradycardia episodes in preterm infants
Support during weaning/extubation in neonatal care (as per clinician’s protocol)
Use strictly under physician supervision in hospital/NICU settings
 
How Does Caffeine Citrate Injection Work?
Caffeine citrate blocks adenosine (A1/A2A) receptors in the central nervous system, increasing respiratory drive and sensitivity to CO₂. It enhances diaphragmatic contractility and improves minute ventilation, thereby reducing apnea frequency in preterm infants.
 
FAQs on Caffeine Citrate Injection
1) What is Caffeine Citrate Injection used for?
It is indicated for the treatment of apnea of prematurity in preterm neonates under medical supervision in NICU settings.
2) What strengths and pack sizes are available?
Standard is 20 mg/mL (≈10 mg/mL caffeine base) in 1 mL, 3 mL, or 5 mL Type I glass ampoules/vials; other strengths and packs can be customized.
3) Is the formulation preservative-free?
Yes. We supply preservative-free, sterile single-dose presentations suitable for neonatal use.
4) Do you provide regulatory support and stability data?
Yes. CTD/eCTD dossiers, stability (ICH zones, including IVb), validation and registration assistance are available for targeted markets.
 
Looking for a reliable Caffeine Citrate Injection manufacturer?
Contact Farbe Firma Pvt. Ltd. for dossier support, registration assistance, private labeling, and export supplies.