Dexmedetomidine Hydrochloride Injection is indicated for sedation of non-intubated patients prior to and/or during surgical and other procedures.
Dexmedetomidine Hydrochloride Injection is a central alpha-2 adrenergic agonist indicated for the sedation of non-intubated patients prior to and/or during surgical and other procedures1. Here are some key details about it:
Indications and Usage:
Dexmedetomidine Hydrochloride Injection is used for the sedation of non-intubated patients before and during surgical and other procedures.
It provides a state of conscious sedation while allowing patients to remain responsive and cooperative.
Dosage and Administration:
Dilute the injection in 0.9% Sodium Chloride to achieve a concentration of 4 mcg/mL before administration.
Administer intravenously using a controlled infusion device.
The administration duration should not exceed 24 hours.
Continuously monitor blood pressure, heart rate, and oxygen levels during and after discontinuation.
The recommended loading infusion dosage varies based on the procedure type (more invasive vs. less invasive).
Maintenance infusion dosage ranges from 0.2 to 1 mcg/kg/hour for most procedures.
Geriatric patients (age > 65 years) may require dosage adjustments.
Consider dosage reduction for patients with hepatic impairment1.
Warnings and Precautions:
Bradycardia and Sinus Arrest: Monitor heart rate and consider appropriate interventions.
Hypotension: Monitor blood pressure and adjust fluid administration or use pressor agents as needed.
Transient Hypertension: Observe during loading dose administration.
Dexmedetomidine Hydrochloride Injection is generally well-tolerated, but close monitoring is essential1.
Remember to consult a healthcare professional for personalized advice regarding the use of Dexmedetomidine Hydrochloride Injection. If you have any further questions or need additional information, feel free to ask! 😊