Phytomenadione (Vitamin K1) Injection is used to treat bleeding or blood clotting problems caused by vitamin K deficiency, certain medicines (eg, warfarin), or medical conditions (obstructive jaundice, ulcerative colitis).
Phytomenadione injection, also known as vitamin K1 or phylloquinone, plays a crucial role in the body. Let’s explore more about it:
Indications and Usage:
Phytomenadione is used to treat vitamin K deficiency or interference.
It helps improve conditions caused by low levels of vitamin K, which is essential for blood clotting and bone metabolism12.
Administration:
Routes: Phytomenadione Injectable Emulsion can be administered via intravenous, intramuscular, or subcutaneous routes.
Subcutaneous Route: Whenever possible, it is recommended to administer it subcutaneously.
Intravenous and Intramuscular Routes: These routes should be avoided unless subcutaneous administration is not feasible and the serious risk justifies it3.
Dosage Forms and Strengths:
Available as a 1 mg/0.5 mL single-dose vial and a SAF-T-Jet® vial injector.
Contraindications:
Hypersensitivity: Avoid Phytomenadione if there is hypersensitivity to phytonadione or any other component of the medication.
Warnings and Precautions:
Hypersensitivity Reactions: Fatal and severe hypersensitivity reactions, including anaphylaxis, have occurred with intravenous or intramuscular administration. Dilution to avoid rapid intravenous infusion is recommended3.
Cutaneous Reactions: Be aware of potential cutaneous reactions.
Adverse Reactions:
Hypersensitivity Reactions: These are serious adverse reactions associated with Phytomenadione Injectable Emulsion.
Drug Interactions:
Phytomenadione may induce temporary resistance to prothrombin-depressing anticoagulants, especially when larger doses are used.
Use in Specific Populations:
Pregnancy: Studies have not reported a clear association between phytonadione and adverse developmental outcomes during pregnancy.
Overdosage:
Overdose may result in hemolysis, jaundice, and hyperbilirubinemia, particularly in newborns, especially premature infants.
Description:
Phytonadione is a clear, yellow to amber, viscous, odorless or nearly odorless liquid.
Remember to consult your healthcare provider for personalized advice regarding Phytomenadione. If you have any specific questions, feel free to ask! 😊🌟