Sodium Stibogluconate Injection: Cure for Leishmaniasis & Parasitic Diseases
- Farbe Firma Admin
- Jul 10, 2025
- 3 min read
Updated: Jan 26
Last Updated: January 26, 2026
TL;DR (Summary)
Sodium Stibogluconate Injection is a critical pentavalent antimonial medication used primarily to treat visceral, cutaneous, and mucocutaneous leishmaniasis. It functions by inhibiting the energy metabolism of the Leishmania parasite, leading to its elimination. As a leading manufacturer, Farbe Firma produces high-quality, WHO-GMP compliant formulations to support global health initiatives against these neglected tropical diseases.
Key Takeaways
Primary Use: First-line treatment for Visceral Leishmaniasis (Kala-azar).
Mechanism: Disrupts parasite bioenergetics by inhibiting glycolysis and ATP phosphorylation.
Dosage: Typically administered at 20 mg/kg/day via IM or IV routes.
Availability: Manufactured by Farbe Firma under strict global regulatory standards.
Efficacy: Highly effective against antimony-sensitive strains of Leishmania.
Table of Contents
What is Sodium Stibogluconate Injection?
Sodium Stibogluconate Injection is a potent antiparasitic medication essential for treating various forms of leishmaniasis. This pentavalent antimonial compound works effectively by targeting the parasitic enzymes responsible for energy production. Doctors prescribe it primarily for visceral leishmaniasis, also known as Kala-azar, in endemic regions worldwide. It remains a vital drug in the global fight against neglected tropical diseases.
Mechanism of Action and Therapeutic Uses
Sodium Stibogluconate belongs to the class of pentavalent antimonials, which are chemically stable and effective. The drug is converted into a trivalent form within the parasite, which is toxic to it. This process inhibits the parasite's glycolytic enzymes and fatty acid oxidation, causing bioenergetic collapse.
Primary Indications
Visceral Leishmaniasis (Kala-azar): Treats systemic infections affecting the liver and spleen.
Cutaneous Leishmaniasis: Heals skin lesions and preventing permanent scarring or disfigurement.
Mucocutaneous Leishmaniasis: Addresses infections spreading to the mucous membranes of the nose and mouth.
Quick Inquiry: Need high-quality Sodium Stibogluconate for your region? Request a Quote Here.
Farbe Firma: Leading Sodium Stibogluconate Manufacturer
Farbe Firma Pvt. Ltd. stands as a premier manufacturer of sterile injectable medications in India. We produce Sodium Stibogluconate Injection in our state-of-the-art, WHO-GMP certified manufacturing facility. Our commitment to quality ensures that every vial meets rigorous international pharmacopoeia standards.
Why Partner with Farbe Firma?
Global Reach: We export to Africa, CIS countries, and Latin America reliably. Learn more about our Global Reach.
Regulatory Support: We provide comprehensive dossiers, COPP, and technical documents for seamless registration.
Production Capacity: Our facility handles large-volume orders for government tenders and NGOs.
Contract Manufacturing: We offer private labeling services for global pharmaceutical brands.
Dosage, Administration, and Side Effects
Healthcare professionals must administer this medication under strict medical supervision to ensure patient safety.
Recommended Dosage
Standard Dose: 20 mg/kg body weight per day, usually for 20–28 days.
Route: Intramuscular (IM) injection or slow Intravenous (IV) infusion.
Maximum Dose: Historically limited, but modern protocols often recommend full weight-based dosing.
Potential Side Effects
Common: Injection site pain, anorexia, nausea, vomiting, and muscle pain (myalgia).
Serious: Pancreatitis, cardiac arrhythmias (QT prolongation), or elevated liver enzymes.
Monitoring: Regular cardiac (ECG) and hepatic function monitoring is essential during treatment.
Frequently Asked Questions (FAQs)
What is Sodium Stibogluconate Injection used for?
It is primarily used to treat three forms of Leishmaniasis: visceral (Kala-azar), cutaneous, and mucocutaneous. It effectively eliminates the Leishmania parasite from the patient’s system.
How does Sodium Stibogluconate kill parasites?
The drug inhibits the parasite's glycolysis and fatty acid oxidation processes. This blocks the formation of ATP and GTP, effectively starving the parasite of energy.
Is Farbe Firma a WHO-GMP certified manufacturer?
Yes, Farbe Firma Pvt. Ltd. manufactures this injection in a WHO-GMP certified facility. We ensure the highest sterility and quality standards for all our Products.
What are the storage conditions for this injection?
Store the injection below 25°C in a cool, dry place away from light. Do not freeze the solution, as this may compromise its chemical stability.
Can I get a contract manufacturing quote?
Absolutely, we specialize in contract manufacturing and export for global markets. You can contact us directly via our Contact Page for proposals.
Technical Reviewer: This content was medically reviewed by our technical expert team.
Connect with our Director: Maulik Sudani on LinkedIn
Technical Expert: Jignasu Sudani on LinkedIn
External Authority: For more guidelines on Leishmaniasis treatment, visit the World Health Organization (WHO).
Contact Us:
Visit our website: www.farbefirma.org
Know More About Us: About Farbe Firma
Email: director@farbefirma.org
Location: Farbe Firma Pvt Ltd, Gujarat, INDIA.
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